Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943428 | 0.91 | MET (0.44) | MAPTALDH1A1L3MBTL1ALOX15KDM4E | |
| SCHEMBL4211749 | 0.90 | ACKR3 (0.44) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4345582 | 0.88 | HTR4 (0.45) | HTR4MAPTALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL4353016 | 0.88 | HTR4 (0.45) | HTR4MAPTALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL3943966 | 0.82 | RAB9A (0.43) | HTR4ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3941054 | 0.81 | MAPT (0.49) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL3941048 | 0.81 | MAPT (0.49) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL4036176 | 0.81 | ACKR3 (0.44) | HTR4ALDH1A1KMT2AMETPOLB | |
| SCHEMBL3940683 | 0.80 | MAPT (0.50) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL3942936 | 0.79 | MAPT (0.47) | MAPTALDH1A1L3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |