SCHEMBL434845

SCHEMBL434845

CCCCN[Si](C)(C)NCCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
ALDH1A1 P00352 1/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
ADH1B P00325 2/20 0.38
ADH1C P00326 2/20 0.38
ADH1A P07327 2/20 0.38
ADH7 P40394 2/20 0.38
CA12 O43570 1/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38
LMNA P02545 1/20 0.35
EPHX1 P07099 4/20 0.35
ALOX15 P16050 1/20 0.33
THRB P10828 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
ACHE P22303 1/20 0.31
MMP2 P08253 1/20 0.31
ADH4 P08319 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1669042 0.88 EPHX1 (0.50) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL679041 0.81 TSHR (0.43) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL5696489 0.81
SCHEMBL232916 0.80 ADH1B (0.32) CA1ADH1BADH1AADH7
SCHEMBL233914 0.78 TSHR (0.45) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL27395852 0.77
SCHEMBL30746776 0.77 TSHR (0.39) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL28095724 0.75 TSHR (0.38) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL4210461 0.75 TSHR (0.38) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL27515627 0.75 TSHR (0.38) TSHRALDH1A1CA1CA2ADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180135167-A1 Transparent Sheet Materials FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2018-05-17 US claimed
EP-3234216-A2 TRANSPARENT SHEET MATERIALS Fujifilm Manufacturing Europe BV (NL) 2017-10-25 EP claimed
EP-1040165-B1 A POLYSILOXANE HAVING A COPOLYMER DISPERSED THEREIN AND SEALANTS CONTAINING THE SAME TREMCO INC (US) 2002-06-12 EP claimed
EP-0138103-A2 RTV silicone pastes BAYER AG (DE) 1985-04-24 EP claimed
EP-3032296-B1 OPTICAL MEMBER AND METHOD FOR MANUFACTURING OPTICAL MEMBER CANON KK (JP) 2024-08-28 EP disclosed
US-20240030026-A1 PROCESSING METHOD, METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE, PROCESSING APPARATUS, AND RECORDING MEDIUM Kokusai Electric Corporation (JP) 2024-01-25 US disclosed
US-20230068883-A1 A MOISTURE-CURABLE SILICONE ELASTOMER COMPOSITION WACKER CHEMIE AG (DE) 2023-03-02 US disclosed
WO-2022264430-A1 SEMICONDUCTOR DEVICE MANUFACTURING METHOD, SUBSTRATE PROCESSING METHOD, SUBSTRATE PROCESSING DEVICE, AND PROGRAM 株式会社KOKUSAI ELECTRIC 2022-12-22 WO disclosed
EP-3261605-B2 CYCLOOLEFIN POLYMER CONTAINER WITH A SCRATCH RESISTANT AND ANTI-STATIC COATING SIO2 MEDICAL PRODUCTS INC (US) 2022-04-20 EP disclosed
CN-107592807-B Cycloolefin polymer container having a scratch-resistant and antistatic coating SIO2医药产品公司 2022-04-15 CN disclosed
US-11038145-B2 Laminated film and process for manufacturing the same, as well as method for analyzing laminated film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-15 US disclosed
EP-3135745-B1 SEMICONDUCTOR NANOPARTICLE ASSEMBLY AND METHOD FOR PRODUCING SAME KONICA MINOLTA INC (JP) 2021-03-10 EP disclosed
US-5952044-A APPLYING A COATING MANUFACTURED BY APPLICATION AND HARDENING OF A COATING MATERIAL CONTAINING A HYDROLYTIC CONDENSATION PRODUCT COMPRISING A CROSS-LINKABLE ORGANOFUNCTIONAL HYDROSILICON, A METAL COMPOUND AND AN ORGANIC PREPOLYMER FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1999-09-14 US disclosed
EP-0610831-B1 Coating composition and a process for preparing coatings with functional groups FRAUNHOFER GES FORSCHUNG (DE) 1997-08-06 EP disclosed
US-5622784-A WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM SEIKO EPSON CORPORATION (JP) 1997-04-22 US disclosed
EP-0610831-A2 Coating composition and a process for preparing coatings with functional groups FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1994-08-17 EP disclosed
EP-0292138-B1 SILYLAMINES AS ADDITIVES IN GROUP TRANSFER POLYMERIZATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-17 EP disclosed
EP-0292138-A1 Silylamines as additives in group transfer polymerization E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-23 EP disclosed
US-4771116-A SCAVENGERS FOR REACTIVE POISONS, I.E. HYDROXYL-CONTAINING SUBSTANCES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-13 US disclosed
US-4555420-A DIFUNCTIONAL NITROGEN-CONTAINING SILANE CURING AGENTS; LOW MODULUS ENCAPPED POLYSILOXANES GENERAL ELECTRIC COMPANY (US) 1985-11-26 US disclosed