Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13810416 | 0.93 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP2C19CYP1A2KDM4ECYP2D6 | |
| SCHEMBL4336515 | 0.90 | LDHA (0.48) | SMN1; SMN2KDM4EOPRK1ALDH1A1MAPT | |
| SCHEMBL4335057 | 0.89 | KDM4E (0.44) | SMN1; SMN2CYP2C19CYP1A2KDM4ECYP2D6 | |
| SCHEMBL4335802 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP2C19CYP1A2KDM4ECYP2D6 | |
| SCHEMBL4332405 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP2C19CYP1A2KDM4ECYP2D6 | |
| SCHEMBL4339592 | 0.87 | KDM4E (0.46) | SMN1; SMN2CYP2C19CYP1A2KDM4ECYP2D6 | |
| SCHEMBL6686370 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP2C19CYP1A2KDM4ECYP2D6 | |
| SCHEMBL4335031 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2CYP2C19CYP1A2KDM4ECYP2D6 | |
| SCHEMBL13810388 | 0.84 | ADRB2 (0.45) | SMN1; SMN2CYP2C19CYP1A2KDM4EOPRK1 | |
| SCHEMBL4341241 | 0.82 | KDM4E (0.44) | CYP2C19KDM4ECYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
| EP-1380562-A1 | CARBOXYLIC ACID DERIVATIVE AND SALT THEREOF | Eisai Co., Ltd. (JP) | 2004-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | GPR119, IRS1, SLC5A1 | SMN1; SMN2 3054/4885CYP2C19 2209/4885CYP1A2 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.