Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL434848

C=C(c1ccccc1)c1ccccc1.N.N

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
MAPT P10636 3/20 0.50
HSD17B10 Q99714 2/20 0.50
HTT P42858 1/20 0.50
GFER P55789 1/20 0.50
GPR55 Q9Y2T6 1/20 0.50
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
TSHR P16473 2/20 0.45
DAO P14920 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
AKT1 P31749 1/20 0.42
F2 P00734 1/20 0.41
F10 P00742 1/20 0.41
F12 P00748 1/20 0.41
F7 P08709 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28340939 0.97 MEN1 (0.61) MEN1KMT2AMAPTHSD17B10HTT
SCHEMBL7930063 0.97 MEN1 (0.61) MEN1KMT2AMAPTHSD17B10HTT
SCHEMBL3844822 0.97 MEN1 (0.61) MEN1KMT2AMAPTHSD17B10HTT
SCHEMBL26736 0.97 MEN1 (0.61) MEN1KMT2AMAPTHSD17B10HTT
Benzene SCHEMBL9731493 0.97 MEN1 (0.61) MEN1KMT2AMAPTHSD17B10HTT
SCHEMBL894135 0.93 MEN1 (0.65) MEN1KMT2AMAPTHSD17B10HTT
Hydrochloric Acid SCHEMBL10598447 0.93 KMT2A (0.58) MEN1KMT2AMAPTHSD17B10HTT
SCHEMBL8210944 0.93 MEN1 (0.58) MEN1KMT2AMAPTHSD17B10HTT
Ethylene SCHEMBL6524259 0.93 MEN1 (0.58) MEN1KMT2AMAPTHSD17B10HTT
SCHEMBL11434494 0.93 MEN1 (0.58) MEN1KMT2AMAPTHSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977978-A Catalytic synthesis method of chiral pyrazolo hydro-pyran compound 中国海洋大学 2025-05-13 CN claimed
CN-117926354-A Pulse cyanide-free gold electroplating liquid and electroplating method thereof 深圳市联合蓝海应用材料科技股份有限公司 2024-04-26 CN claimed
EP-3074116-A1 FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING B.G. Negev Technologies and Applications Ltd. (IL) 2016-10-05 EP claimed
US-9446393-B2 Transition metal complexes for enantioselective catalysis of carbon-carbon, carbon-heteroatom, and carbon-hydrogen bond forming reactions THE TEXAS A&M UNIVERSITY SYSTEM (US) 2016-09-20 US claimed
US-20150165429-A1 TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2015-06-18 US claimed
WO-2015079442-A1 FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD (IL) 2015-06-04 WO claimed
WO-2014018978-A2 TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2014-01-30 WO claimed
JP-10068722-A None JP disclosed
US-20250382392-A1 AMIDE LINKAGES OF SUGAR MOIETIES TO AMINE TERMINATED LEASHES ATTACHED TO CARBOHYDRATE POLYMERS NAVIDEA BIOPHARMACEUTICALS INC (US) 2025-12-18 US disclosed
US-12404349-B2 Amide linkages of sugar moieties to amine terminated leashes attached to carbohydrate polymers NAVIDEA BIOPHARMACEUTICALS, INC. (US) 2025-09-02 US disclosed
EP-4598583-A2 AMIDE LINKAGES OF SUGAR MOIETIES TO AMINE TERMINATED LEASHES ATTACHED TO CARBOHYDRATE POLYMERS Navidea Biopharmaceuticals, Inc. (US) 2025-08-13 EP disclosed
US-20250009892-A1 DELIVERY SYSTEMS AND METHODS FOR REACTIVE HYDROXYL-CONTAINING COMPOUNDS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2025-01-09 US disclosed
US-12178829-B2 Altering net charge on mannosylated dextrans to maximize target tissue uptake and off target competitive blocking NAVIDEA BIOPHARMACEUTICALS, INC. (US) 2024-12-31 US disclosed
EP-0586520-A1 BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGS ISIS PHARMACEUTICALS, INC. (US) 1994-03-16 EP disclosed
EP-0586570-A1 BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGUES ISIS PHARMACEUTICALS, INC. (US) 1994-03-16 EP disclosed
WO-1992020822-A1 BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGUES ISIS PHARMACEUTICALS, INC. (US) 1992-11-26 WO disclosed
WO-1992020823-A1 BACKBONE MODIFIED OLIGONUCLEOTIDE ANALOGS ISIS PHARMACEUTICALS, INC. (US) 1992-11-26 WO disclosed
EP-0129527-B1 VULCANISABLE RUBBER COMPOSITION AND COMPOUNDS USEFUL AS STABILISING AGENTS FOR RUBBER VULCANISATES MONSANTO EUROPE S.A./N.V. (BE) 1989-07-12 EP disclosed
EP-0109955-B1 RUBBER/METAL COMPOSITES MONSANTO EUROPE S.A./N.V. (BE) 1988-01-20 EP disclosed
EP-0070143-B1 ORGANIC THIOSULPHATES AND THIOSULPHONATES USEFUL AS STABILISING AGENTS FOR RUBBER VULCANISATES MONSANTO EUROPE S.A./N.V. (BE) 1985-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12178829-B2 Altering net charge on mannosylated dextrans to maximize target tissue uptake and off target competitive blocking CD209, FUT6, SIGLEC7 MEN1 284/4885KMT2A 3751/4885MAPT 2668/4885
US-12404349-B2 Amide linkages of sugar moieties to amine terminated leashes attached to carbohydrate polymers MASP2, CLEC4M, GALR3 MEN1 2055/4885KMT2A 2195/4885MAPT 2751/4885
US-20250382392-A1 AMIDE LINKAGES OF SUGAR MOIETIES TO AMINE TERMINATED LEASHES ATTACHED TO CARBOHYDRATE POLYMERS MASP2, CLEC4M, GALR3 MEN1 2055/4885KMT2A 2195/4885MAPT 2751/4885
US-20150165429-A1 TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS SOD1, YWHAZ, L1CAM MEN1 3811/4885KMT2A 840/4885MAPT 4214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.