Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 10/20 | 0.47 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635089 | 1.00 | CA1 (0.51) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL12635086 | 1.00 | CA1 (0.51) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL6973040 | 0.87 | CA1 (0.46) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL1992684 | 0.85 | CA1 (0.51) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL1991718 | 0.85 | CA1 (0.51) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL1991716 | 0.85 | CA1 (0.51) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL23989482 | 0.84 | CA1 (0.44) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL29173756 | 0.83 | CTSK (0.54) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL1106536 | 0.82 | CA1 (0.49) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL29610548 | 0.82 | CA1 (0.49) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080570-B2 | α2B and α2C agonists | ALLERGAN, INC. (US) | 2011-12-20 | — | — | US | disclosed |
| US-20090275627-A1 | ALPHA2B AND ALPHA2C AGONISTS | ALLERGAN, INC. (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275627-A1 | ALPHA2B AND ALPHA2C AGONISTS | ADRA2B, ADRA2C, ADRB2 | CA1 3621/4885CA2 1143/4885CA7 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.