Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | DPP4 | P27487 | 3/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349086 | 1.00 | HTR2A (0.55) | HTR2AHTR2BHTR2CDPP4DPP7 | |
| SCHEMBL4352828 | 0.85 | SLC1A1 (0.51) | DPP4DPP7DPP8DPP9PPARG | |
| SCHEMBL4352830 | 0.85 | SLC1A1 (0.51) | DPP4DPP7DPP8DPP9PPARG | |
| SCHEMBL4349071 | 0.84 | MEN1 (0.41) | LMNAMEN1KMT2A | |
| SCHEMBL4349075 | 0.84 | MEN1 (0.41) | LMNAMEN1KMT2A | |
| SCHEMBL1527219 | 0.83 | EPHX1 (0.48) | EPHX1LMNAOPRK1MEN1KMT2A | |
| SCHEMBL14860145 | 0.83 | EPHX1 (0.48) | EPHX1LMNAOPRK1MEN1KMT2A | |
| SCHEMBL14860143 | 0.83 | EPHX1 (0.48) | EPHX1LMNAOPRK1MEN1KMT2A | |
| SCHEMBL4345868 | 0.82 | PNMT (0.50) | DPP4MEN1KMT2A | |
| SCHEMBL4345865 | 0.82 | PNMT (0.50) | DPP4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |