Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996910 | 0.80 | CYP3A4 (0.36) | GABRA1GABRB2 | |
| SCHEMBL23240333 | 0.77 | GABRA1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL25573712 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL1457358 | 0.76 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL5017628 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL16707524 | 0.74 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL17650996 | 0.72 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL24390818 | 0.72 | RAPGEF4 (0.33) | GABRA1GABRB2 | |
| SCHEMBL4350039 | 0.72 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL24553953 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094677-A1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO-DEGENERATIVE DISEASES | NV Remynd (BE) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008061781-A1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO-DEGENERATIVE DISEASES | NV REMYND (BE) | 2008-05-29 | — | — | WO | disclosed |