SCHEMBL5017628

SCHEMBL5017628

Cc1c(F)cc(N=C=S)c(F)c1F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4350030 0.86 ALDH1A1 (0.31) ALDH1A1LMNA
SCHEMBL5788029 0.80 CYP3A4 (0.45) ALDH1A1
SCHEMBL22602515 0.76 ALDH1A1 (0.30) ALDH1A1LMNA
SCHEMBL4350033 0.76 GABRA1 (0.33)
SCHEMBL15589318 0.75 ALDH1A1 (0.38) ALDH1A1LMNA
SCHEMBL1399737 0.72 ABCB11 (0.34) ALDH1A1
SCHEMBL13788635 0.69 ALDH1A1 (0.34) ALDH1A1LMNA
SCHEMBL17650560 0.69 ALDH1A1 (0.37) ALDH1A1LMNA
SCHEMBL30940600 0.68 ALDH1A1 (0.36) ALDH1A1
SCHEMBL3229637 0.68 ALDH1A1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1311475-B1 AMINOCYCLOHEXANE DERIVATIVES HOFFMANN LA ROCHE (CH) 2008-08-06 EP disclosed