SCHEMBL435004

SCHEMBL435004

Cc1cccc2nccnc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 2/20 0.54
MEN1 O00255 1/20 0.54
USP2 O75604 1/20 0.54
POLB P06746 1/20 0.54
KMT2A Q03164 1/20 0.54
HSD17B10 Q99714 1/20 0.50
PRMT5 O14744 1/20 0.46
HTR1A P08908 1/20 0.44
ADRA1D P25100 1/20 0.44
ADRA1A P35348 1/20 0.44
ADRA1B P35368 1/20 0.44
LMNA P02545 1/20 0.41
ESR1 P03372 1/20 0.41
PKM P14618 1/20 0.41
TSHR P16473 1/20 0.41
PSMD14 O00487 1/20 0.39
COPS5 Q92905 1/20 0.39
CCR1 P32246 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29832653 1.00 MAPT (0.54) MAPTALDH1A1KDM4EMEN1USP2
SCHEMBL1773094 0.84 PRMT5 (0.53) MAPTALDH1A1KDM4EMEN1USP2
SCHEMBL10022978 0.80 MAPT (0.44) MAPTALDH1A1KDM4EMEN1USP2
SCHEMBL9124792 0.78 MAPT (0.36) MAPTALDH1A1KDM4EMEN1USP2
SCHEMBL21591589 0.77 PARP1 (0.35) MAPTALDH1A1KDM4EMEN1USP2
SCHEMBL29463681 0.76 MAPT (0.50) MAPTALDH1A1KDM4EMEN1USP2
SCHEMBL87693 0.76 MAPT (0.50) MAPTALDH1A1KDM4EMEN1USP2
SCHEMBL30335572 0.76 MAPT (0.50) MAPTALDH1A1KDM4EMEN1USP2
Quinoline SCHEMBL28253161 0.76 ALDH1A1 (0.63) MAPTALDH1A1KDM4EPOLBPRMT5
SCHEMBL3069598 0.75 KDM4E (0.58) MAPTALDH1A1KDM4EMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 964 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 US claimed
CN-113905612-B Arthropod control composition 弗门尼舍有限公司 2025-04-08 CN claimed
CN-116268351-B Hazelnut-flavor essence base material and preparation method and application thereof 湖南嘉利香料有限公司 2025-02-18 CN claimed
CN-116268351-A Hazelnut-flavor essence base material and preparation method and application thereof 湖南嘉利香料有限公司 2023-06-23 CN claimed
CN-114805225-B Hydrogenation method of methyl quinoxaline 苏州中车氢能动力技术有限公司 2022-09-23 CN claimed
CN-114805225-A Hydrogenation method of methyl quinoxaline 苏州中车氢能动力技术有限公司 2022-07-29 CN claimed
US-11365370-B2 Fragrance compositions THE PROCTER & GAMBLE COMPANY (US) 2022-06-21 US claimed
US-20220142158-A1 ARTHROPOD CONTROL COMPOSITIONS FIRMENICH SA (CH) 2022-05-12 US claimed
US-20220142157-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH SA (CH) 2022-05-12 US claimed
CN-113905612-A Arthropod control composition 弗门尼舍有限公司 2022-01-07 CN claimed
EP-2091929-A1 AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS The European Molecular Biology Laboratory (DE) 2009-08-26 EP claimed
EP-1758905-B1 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINE, THE PRODUCTION THEREOF AND THE USE IN THE FORM OF A DDP-IV INHIBITOR BOEHRINGER INGELHEIM INT (DE) 2009-04-29 EP claimed
CN-101421257-A Agents that disrupt cellular replication and their use in inhibiting pathological conditions EUROPEAN MOLECULAR BIOLOGY LAB EMBL (DE) 2009-04-29 CN claimed
WO-2009024542-A2 PURIN DERIVATIVES FOR USE IN THE TREATMENT OF FAB-RELATED DISEASES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-02-26 WO claimed
EP-1515681-B1 NON-CRYSTALLINE PERFUME OR FLAVOUR DELIVERY SYSTEM FIRMENICH & CIE (CH) 2008-09-24 EP claimed
WO-2007107352-A1 AGENTS THAT DISRUPT CELLULAR REPLICATION AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS THE EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2007-09-27 WO claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION CNOT9, MSL1, MT-CO2 MAPT 4191/4885ALDH1A1 3224/4885KDM4E 1705/4885
US-20220142157-A1 ARTHROPOD CONTROLLING COMPOSITION AGO2, NOP2, FBL MAPT 2538/4885ALDH1A1 3272/4885KDM4E 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.