Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 1/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608193 | 0.82 | LMNA (0.62) | ALDH1A1GAASMN1; SMN2NPC1HPGD | |
| SCHEMBL27734537 | 0.81 | CA9 (0.50) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL27734539 | 0.81 | CA9 (0.50) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL27754918 | 0.80 | KEAP1 (0.61) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL5607840 | 0.80 | KEAP1 (0.61) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL5607879 | 0.80 | ALDH1A1 (0.54) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL27755098 | 0.80 | ALDH1A1 (0.54) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL8232101 | 0.79 | TSHR (0.67) | ALDH1A1SMN1; SMN2HPGDCA2TPH1 | |
| SCHEMBL5079182 | 0.79 | MMP2 (0.56) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL19899916 | 0.79 | SLC7A5 (0.61) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028195-A2 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX, INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| EP-1828224-A4 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX INC (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2008077079-A1 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX, INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| EP-1828224-A2 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | Ambrx, Inc. (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006069246-A2 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES | AMBRX, INC. (US) | 2006-06-29 | — | — | WO | disclosed |