Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14975620 | 0.85 | PTPRC (0.36) | CYP1A2CYP2C9CYP2C19TDP1PTGS1 | |
| SCHEMBL435178 | 0.82 | NOTUM (0.33) | NOTUMPDK2IDO1KDM4EALDH1A1 | |
| SCHEMBL8129041 | 0.82 | PTGS1 (0.38) | CYP1A2CYP2C9CYP2C19TDP1PTGS1 | |
| SCHEMBL2316025 | 0.82 | PLA2G7 (0.34) | CYP1A2CYP2C9PTGS1HSD11B1ELANE | |
| SCHEMBL435281 | 0.79 | KMO (0.34) | HSD11B1 | |
| SCHEMBL433503 | 0.79 | MAPK14 (0.34) | IDO1KDM4EALDH1A1 | |
| SCHEMBL8986646 | 0.78 | CYP2A6 (0.38) | CYP1A2CYP2C9CYP2C19TDP1SMARCA2 | |
| SCHEMBL432908 | 0.76 | PTGS1 (0.34) | PTGS1SMARCA2SMARCA4PBRM1HSD11B1 | |
| SCHEMBL15520665 | 0.74 | CYP1A2 (0.34) | CYP1A2CYP2C9CYP2C19TDP1HSD11B1 | |
| SCHEMBL31067193 | 0.74 | PBRM1 (0.44) | CYP1A2CYP2C9CYP2C19TDP1SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |