⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27510365 | 0.74 | — | — | |
| SCHEMBL8698383 | 0.74 | PARP1 (0.41) | — | |
| SCHEMBL27831516 | 0.73 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL3273322 | 0.73 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL780236 | 0.73 | — | — | |
| SCHEMBL114011 | 0.73 | — | — | |
| Water SCHEMBL29957253 | 0.71 | NAMPT (0.45) | — | |
| Hydrochloric Acid SCHEMBL16239625 | 0.71 | NAMPT (0.45) | — | |
| SCHEMBL2574438 | 0.71 | NAMPT (0.45) | — | |
| SCHEMBL28415921 | 0.70 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021329-A1 | INHIBITORS OF C-FMS KINASE | Janssen Pharmaceutica, N.V. (BE) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007124318-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-01 | — | — | WO | disclosed |