Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921739 | 0.85 | L3MBTL1 (0.43) | KMT2AHPGDALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28291394 | 0.84 | CHRM2 (0.42) | ACHERAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL16825019 | 0.84 | L3MBTL3 (0.59) | ACHE | |
| SCHEMBL969710 | 0.82 | HPGD (0.52) | NPC1GAAKMT2AHPGDALDH1A1 | |
| SCHEMBL1115239 | 0.82 | HPGD (0.47) | NPC1GAAKMT2AHPGDALDH1A1 | |
| SCHEMBL27804524 | 0.81 | LMNA (0.56) | NPC1RAB9AGAAKMT2AHPGD | |
| SCHEMBL2186819 | 0.81 | POLB (0.51) | NPC1RAB9AGRM5KMT2AHPGD | |
| SCHEMBL1642860 | 0.80 | HPGD (0.55) | NPC1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4458413 | 0.80 | PDK2 (0.43) | ACHENPC1RAB9AGRM5HPGD | |
| SCHEMBL2887644 | 0.80 | L3MBTL3 (0.62) | KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |