Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921739 | 0.85 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2ALDH1A1MEN1HPGD | |
| SCHEMBL4352484 | 0.84 | ACHE (0.59) | ACHESMN1; SMN2ALDH1A1RAB9AHPGD | |
| SCHEMBL969710 | 0.82 | HPGD (0.52) | ALDH1A1MEN1HPGDTSHRKMT2A | |
| SCHEMBL1115239 | 0.82 | HPGD (0.47) | SMN1; SMN2ALDH1A1MEN1HPGDTSHR | |
| SCHEMBL16825019 | 0.81 | L3MBTL3 (0.59) | EPHX1ACHEPARP1L3MBTL3L3MBTL1 | |
| SCHEMBL1642860 | 0.80 | HPGD (0.55) | L3MBTL1SMN1; SMN2ALDH1A1MEN1HPGD | |
| SCHEMBL4458413 | 0.80 | PDK2 (0.43) | CHRM2CHRM1EPHX1ACHERAB9A | |
| SCHEMBL2887644 | 0.80 | L3MBTL3 (0.62) | L3MBTL3L3MBTL1TP53BP1ALDH1A1MEN1 | |
| SCHEMBL28799044 | 0.78 | KDM1A (0.42) | ALDH1A1KDM1AMEN1HPGDKMT2A | |
| SCHEMBL1566654 | 0.78 | SIGMAR1 (0.57) | PARP1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104350055-B | Bicyclic heteroaryl derivatives and application thereof as MNK1 and MNK2 regulator | 新加坡科技研究局 | 2019-05-31 | — | — | CN | disclosed |