Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25063097 | 0.85 | CYP2C19 (0.49) | KDM4EPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL74375 | 0.83 | TSHR (0.49) | KDM4EPOLBATMALDH1A1HPGD | |
| SCHEMBL9890035 | 0.80 | RXFP1 (0.46) | KDM4EPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL8335906 | 0.80 | ITGB1 (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL1509182 | 0.79 | GAA (0.41) | KDM4EALDH1A1HPGDHSD17B10ALOX12 | |
| SCHEMBL29811031 | 0.78 | MGLL (0.39) | KDM4EPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL21668622 | 0.78 | KDM4E (0.35) | KDM4EPOLBATMALDH1A1HPGD | |
| SCHEMBL5303474 | 0.78 | ALDH1A1 (0.48) | KDM4EPOLBALDH1A1HPGDALOX12 | |
| SCHEMBL8540066 | 0.78 | TSHR (0.50) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL30505257 | 0.77 | CYP1A2 (0.46) | KDM4EALDH1A1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053403-A2 | Affinity fishing for ligands and proteins receptors | Novo Nordisk A/S (DK) | 2009-04-29 | — | — | EP | disclosed |
| EP-1588173-B1 | AFFINITY FISHING FOR LIGANDS AND PROTEINS RECEPTORS | NOVO NORDISK AS (DK) | 2008-11-26 | — | — | EP | disclosed |
| US-20060257875-A1 | Affinity screening using \"one-bead-one-compound\" libraries | CARLSBERG A/S (DK) | 2006-11-16 | — | — | US | disclosed |
| US-20060003376-A1 | Non-destructive quality control method for microarray substrate coatings via labeled doping | CONZONE SAMUEL D | 2006-01-05 | — | — | US | disclosed |
| US-20040142379-A1 | Affinity fishing for ligands and proteins receptors | CARLSBERG RESEARCH LABORATORY (DK) | 2004-07-22 | — | — | US | disclosed |