Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9890035 | 0.78 | RXFP1 (0.46) | KDM4EALDH1A1HPGDHSD17B10ADRA1A | |
| SCHEMBL4352600 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10ADRA1A | |
| SCHEMBL25063097 | 0.76 | CYP2C19 (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL25063427 | 0.75 | ADRA1A (0.41) | KDM4EALDH1A1HPGDHSD17B10ADRA1A | |
| SCHEMBL74375 | 0.73 | TSHR (0.49) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL8341133 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1POLBSMN1; SMN2TSHR | |
| SCHEMBL8335906 | 0.70 | ITGB1 (0.43) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1509182 | 0.70 | GAA (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL29811031 | 0.69 | MGLL (0.39) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL5303474 | 0.69 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200038383-A1 | IMMEDIATE-RELEASE ABUSE DETERRENT COMPOSITIONS OR MEDICAMENTS FOR TREATING PAIN, ADD, ADHD AND OTHER SYNDROMES OR DISORDERS | ALTER DOMUS (US) LLC | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200038383-A1 | IMMEDIATE-RELEASE ABUSE DETERRENT COMPOSITIONS OR MEDICAMENTS FOR TREATING PAIN, ADD, ADHD AND OTHER SYNDROMES OR DISORDERS | OPRK1, OPRL1, OPRD1 | KDM4E 3455/4885ALDH1A1 45/4885HPGD 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.