Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586034 | 0.90 | ABL1 (0.46) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL4540972 | 0.90 | GPR119 (0.47) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL4524446 | 0.89 | GPR119 (0.40) | GPR119 | |
| SCHEMBL4536702 | 0.88 | GPR119 (0.49) | PTPN2PTPN1PTPN6GPR119USP30 | |
| SCHEMBL4353381 | 0.88 | GPR119 (0.54) | PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL4356480 | 0.88 | GPR119 (0.38) | PTPN1GPR119HDAC4 | |
| SCHEMBL4347885 | 0.86 | GPR119 (0.37) | PTPN2PTPN1GPR119HDAC4 | |
| SCHEMBL4353589 | 0.86 | PTPN2 (0.48) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL4360506 | 0.86 | GPR119 (0.47) | PTPN2PTPN1PTPN6GPR119USP30 | |
| SCHEMBL4356470 | 0.86 | GPR119 (0.38) | ABL1RIN1GPR119HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |