SCHEMBL435340

SCHEMBL435340

CON=C(COc1ccc(COc2ccc(CCC(=O)O)c(F)c2)cc1OC)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 17/20 0.53
FFAR4 Q5NUL3 1/20 0.52
RXRG P48443 2/20 0.47
PPARD Q03181 2/20 0.45
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435339 1.00 FFAR1 (0.53) FFAR1FFAR4RXRGPPARDRXRA
SCHEMBL15239689 0.92 FFAR1 (0.49) FFAR1FFAR4RXRGPPARD
SCHEMBL15239688 0.92 FFAR1 (0.49) FFAR1FFAR4RXRGPPARD
SCHEMBL22668237 0.90 FFAR1 (0.49) FFAR1FFAR4PPARD
SCHEMBL434057 0.89 FFAR1 (0.61) FFAR1FFAR4
SCHEMBL434058 0.89 FFAR1 (0.61) FFAR1FFAR4
SCHEMBL435299 0.84 FFAR1 (0.55) FFAR1FFAR4
SCHEMBL436122 0.84 FFAR1 (0.60) FFAR1FFAR4
SCHEMBL436123 0.84 FFAR1 (0.60) FFAR1FFAR4
SCHEMBL435298 0.84 FFAR1 (0.55) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278915-B2 Agonists of GPR40 CONNEXIOS LIFE SCIENCES PVT LTD (IN) 2016-03-08 US disclosed
US-20130237571-A1 AGONISTS OF GPR40 Conexios Life Sciences PVT. LTD. (IN) 2013-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130237571-A1 AGONISTS OF GPR40 GPR65, GPR55, GPR68 FFAR1 24/4885FFAR4 26/4885RXRG 254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.