Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347874 | 0.87 | KDM1A (0.41) | KDM1AMAOAMAOBBRD4USP30 | |
| SCHEMBL4360375 | 0.85 | KDM1A (0.39) | KDM1AMAOAMAOBBRD4USP30 | |
| SCHEMBL4347925 | 0.84 | USP30 (0.40) | KDM1AMAOAMAOBBRD4USP30 | |
| SCHEMBL4531768 | 0.84 | KDM1A (0.38) | KDM1AMAOAMAOBUSP30PIK3CA | |
| SCHEMBL4347838 | 0.81 | NAMPT (0.44) | HRH3CA1CA2CA9TP53 | |
| SCHEMBL4537918 | 0.80 | PTPN2 (0.43) | CA1CA2CA9ALDH1A1PIK3CA | |
| SCHEMBL4349922 | 0.80 | PTPN2 (0.43) | CA1CA2CA9ALDH1A1PIK3CA | |
| SCHEMBL4356473 | 0.80 | PTPN2 (0.43) | CA1CA2CA9ALDH1A1PIK3CA | |
| SCHEMBL4354214 | 0.80 | FKBP1A (0.42) | TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL4529650 | 0.80 | KMT2A (0.39) | KDM1AMAOAMAOBUSP30KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |