Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347874 | 0.89 | KDM1A (0.41) | KDM1AMAOAMAOBUSP30GPR119 | |
| SCHEMBL4360375 | 0.86 | KDM1A (0.39) | KDM1AMAOAMAOBUSP30GPR119 | |
| SCHEMBL4347925 | 0.86 | USP30 (0.40) | KDM1AMAOAMAOBUSP30DPP4 | |
| SCHEMBL4353455 | 0.84 | KDM1A (0.43) | KDM1AMAOAMAOBUSP30GPR119 | |
| SCHEMBL4354214 | 0.83 | FKBP1A (0.42) | MEN1KMT2A | |
| SCHEMBL4353796 | 0.83 | GPR119 (0.55) | GPR119 | |
| SCHEMBL4349922 | 0.82 | PTPN2 (0.43) | CYP3A4SLC9A1PIK3CA | |
| SCHEMBL4356473 | 0.82 | PTPN2 (0.43) | CYP3A4SLC9A1PIK3CA | |
| SCHEMBL4537918 | 0.82 | PTPN2 (0.43) | CYP3A4SLC9A1PIK3CA | |
| SCHEMBL4529650 | 0.81 | KMT2A (0.39) | KDM1AMAOAMAOBUSP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |