Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347874 | 0.86 | KDM1A (0.41) | KMT2AMEN1KDM1AMAOAMAOB | |
| SCHEMBL4360375 | 0.82 | KDM1A (0.39) | KMT2AMEN1KDM1AMAOAMAOB | |
| SCHEMBL4347925 | 0.82 | USP30 (0.40) | KDM1AMAOAMAOBGPR119USP30 | |
| SCHEMBL4531768 | 0.81 | KDM1A (0.38) | KMT2AMEN1KDM1AMAOAMAOB | |
| SCHEMBL4353455 | 0.80 | KDM1A (0.43) | KMT2AMEN1KDM1AMAOAMAOB | |
| SCHEMBL4356489 | 0.79 | ALDH1A1 (0.43) | KMT2AALDH1A1USP30 | |
| SCHEMBL4353588 | 0.79 | PIK3CA (0.43) | GPR119USP30PIK3CA | |
| SCHEMBL4537918 | 0.78 | PTPN2 (0.43) | POLBALDH1A1PIK3CA | |
| SCHEMBL4349922 | 0.78 | PTPN2 (0.43) | POLBALDH1A1PIK3CA | |
| SCHEMBL4356473 | 0.78 | PTPN2 (0.43) | POLBALDH1A1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |