Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | USP9X | Q93008 | 6/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347925 | 0.87 | USP30 (0.40) | DPP4DPP7USP30NPY2REPHX2 | |
| SCHEMBL4349922 | 0.86 | PTPN2 (0.43) | CYP3A4TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4356473 | 0.86 | PTPN2 (0.43) | CYP3A4TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4537918 | 0.86 | PTPN2 (0.43) | CYP3A4TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4362452 | 0.85 | EPHX2 (0.37) | DPP4USP30NPY2REPHX2AKR1C3 | |
| SCHEMBL4355152 | 0.84 | CHRM2 (0.38) | USP30ALDH1A1SMN1; SMN2 | |
| SCHEMBL4347874 | 0.83 | KDM1A (0.41) | USP30EPHX2 | |
| SCHEMBL4526460 | 0.82 | SMN1; SMN2 (0.43) | NPY2RSMN1; SMN2 | |
| SCHEMBL4347963 | 0.81 | NPC1 (0.46) | TSHRAKR1C1ALDH1A1 | |
| SCHEMBL4356151 | 0.81 | GAA (0.42) | EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |