Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537918 | 0.91 | PTPN2 (0.43) | PIK3CAPTPN2PTPN1LMNAHTT | |
| SCHEMBL4349922 | 0.91 | PTPN2 (0.43) | PIK3CAPTPN2PTPN1LMNAHTT | |
| SCHEMBL4356473 | 0.91 | PTPN2 (0.43) | PIK3CAPTPN2PTPN1LMNAHTT | |
| SCHEMBL4347925 | 0.88 | USP30 (0.40) | EPHX2EPHX1KCNH2USP30PIK3CA | |
| SCHEMBL4353464 | 0.85 | CYP3A4 (0.37) | EPHX2USP30NPY2RAKR1C3AKR1C1 | |
| SCHEMBL4360055 | 0.84 | ALDH1A1 (0.40) | PIK3CADPP4PTPN2PTPN1LMNA | |
| SCHEMBL4347963 | 0.83 | NPC1 (0.46) | PIK3CAAKR1C1PTGS2LMNAHTT | |
| SCHEMBL4347874 | 0.83 | KDM1A (0.41) | EPHX2USP30PIK3CAGPR119 | |
| SCHEMBL4355152 | 0.83 | CHRM2 (0.38) | USP30PIK3CALMNASMN1; SMN2 | |
| SCHEMBL4353588 | 0.83 | PIK3CA (0.43) | EPHX2USP30PIK3CAGPR119LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |