Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ADAMTS7 | Q9UKP4 | 3/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356468 | 0.92 | PTPN2 (0.40) | PTPN2PTPN1CA12CA1CA2 | |
| SCHEMBL4349922 | 0.87 | PTPN2 (0.43) | PTPN2PTPN1CA12CA1CA2 | |
| SCHEMBL4537918 | 0.87 | PTPN2 (0.43) | PTPN2PTPN1CA12CA1CA2 | |
| SCHEMBL4356473 | 0.87 | PTPN2 (0.43) | PTPN2PTPN1CA12CA1CA2 | |
| SCHEMBL4520212 | 0.84 | PTPN2 (0.47) | PTPN2PTPN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4355595 | 0.82 | POLB (0.54) | PTPN2PTPN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4360055 | 0.82 | ALDH1A1 (0.40) | PTPN2PTPN1SMN1; SMN2LMNAHTT | |
| SCHEMBL4357579 | 0.81 | PTPN2 (0.44) | PTPN2PTPN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13586029 | 0.81 | PTPN2 (0.44) | PTPN2PTPN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13586060 | 0.80 | SMN1; SMN2 (0.47) | PTPN2PTPN1SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |