Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537918 | 0.93 | PTPN2 (0.43) | ALDH1A1SLC9A1PTPN2PTPN1CYP2C19 | |
| SCHEMBL4356473 | 0.93 | PTPN2 (0.43) | ALDH1A1SLC9A1PTPN2PTPN1CYP2C19 | |
| SCHEMBL4349922 | 0.93 | PTPN2 (0.43) | ALDH1A1SLC9A1PTPN2PTPN1CYP2C19 | |
| SCHEMBL4353588 | 0.85 | PIK3CA (0.43) | SLC9A1LMNAPIK3CA | |
| SCHEMBL4355595 | 0.84 | POLB (0.54) | ALDH1A1PTPN2PTPN1CYP2C19LMNA | |
| SCHEMBL4520212 | 0.84 | PTPN2 (0.47) | ALDH1A1PTPN2PTPN1CYP2C19LMNA | |
| SCHEMBL4362452 | 0.84 | EPHX2 (0.37) | PTPN2PTPN1LMNASMN1; SMN2HTT | |
| SCHEMBL13586033 | 0.84 | LMNA (0.45) | SLC9A1GAACYP2C19ADAMTS7ADAMTS5 | |
| SCHEMBL4347963 | 0.83 | NPC1 (0.46) | ALDH1A1LMNATSHRMGLLHTT | |
| SCHEMBL4356468 | 0.82 | PTPN2 (0.40) | ALDH1A1PTPN2PTPN1CYP2C19ADAMTS7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |