Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | F13A1 | P00488 | 1/20 | 0.57 |
| ▸ | ESRRB | O95718 | 2/20 | 0.52 |
| ▸ | ESRRG | P62508 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835177 | 0.85 | LMNA (0.57) | GAAGFERNPC1CYP1A2CYP2D6 | |
| SCHEMBL6312788 | 0.85 | HPGD (0.60) | NPC1RAB9APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL2265490 | 0.85 | MCL1 (0.70) | MCL1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29249541 | 0.83 | MCL1 (0.72) | MCL1GAATRPV1 | |
| SCHEMBL14370357 | 0.82 | KDM4E (0.69) | KDM4EF13A1ESRRBESRRGGAA | |
| SCHEMBL8579571 | 0.79 | P2RY6 (0.51) | MCL1MAPT | |
| SCHEMBL2379821 | 0.79 | KDM4E (0.65) | KDM4EF13A1ESRRBESRRGGAA | |
| SCHEMBL28747980 | 0.79 | KDM4E (0.65) | KDM4EF13A1ESRRBESRRGGAA | |
| SCHEMBL4161209 | 0.79 | ESRRB (0.77) | KDM4EF13A1ESRRBESRRGGAA | |
| SCHEMBL2191045 | 0.79 | KDM4E (0.65) | KDM4EF13A1ESRRBESRRGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10106565-B2 | Phosphorylated dendrimers as antiinflammatory drugs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-10-23 | — | — | US | disclosed |
| US-8815834-B2 | Use of dendrimers to stimulate cell growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-08-26 | — | — | US | disclosed |
| US-8815834-B2 | Use of dendrimers to stimulate cell growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-08-26 | — | — | US | disclosed |
| US-8815834-B2 | Use of dendrimers to stimulate cell growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-08-26 | — | — | US | disclosed |
| US-20130336997-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-19 | — | — | US | disclosed |
| EP-1771548-B1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NAT RECH SCIENT (FR) | 2012-06-27 | — | — | EP | disclosed |
| US-20090142316-A1 | Use of Dendrimers to Stimulate Cell Growth | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-06-04 | — | — | US | disclosed |
| EP-1771548-A1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006024769-A1 | USE OF DENDRIMERS TO STIMULATE CELL GROWTH | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-03-09 | — | — | WO | disclosed |
| WO-1997023202-A1 | SUBTYPE-SELECTIVE NMDA RECEPTOR LIGANDS AND THE USE THEREOF | STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALTH SCIENCES UNIVERSITYA ND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) | 1997-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10106565-B2 | Phosphorylated dendrimers as antiinflammatory drugs | DUSP6, DUSP10, PTMS | KDM4E 3952/4885F13A1 2614/4885ESRRB 1201/4885 |
| US-20090142316-A1 | Use of Dendrimers to Stimulate Cell Growth | HDGF, CD40LG, PPIP5K2 | KDM4E 4303/4885F13A1 737/4885ESRRB 578/4885 |
| US-20130336997-A1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | DUSP6, DUSP10, PTMS | KDM4E 3952/4885F13A1 2614/4885ESRRB 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.