Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354123 | 1.00 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL12443192 | 0.93 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL15600630 | 0.89 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL18717311 | 0.89 | MAPT (0.58) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11429346 | 0.86 | MEN1 (0.63) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL12416679 | 0.84 | SMN1; SMN2 (0.71) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL30342959 | 0.83 | SMN1; SMN2 (0.57) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL12417120 | 0.81 | CA12 (0.66) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL2302287 | 0.79 | KDM4E (0.73) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4348747 | 0.79 | ALDH1A1 (0.79) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475762-B2 | Process for the preparation of urethanes | COVESTRO DEUTSCHLAND AG (DE) | 2016-10-25 | — | — | US | disclosed |
| US-20160152559-A1 | PROCESS FOR THE PREPARATION OF URETHANES | COVESTRO DEUTSCHLAND AG (DE) | 2016-06-02 | — | — | US | disclosed |
| US-9284267-B2 | Process for the preparation of urethanes | BAYER MATERIALSCIENCE AG (DE) | 2016-03-15 | — | — | US | disclosed |
| US-20090275771-A1 | Process for the preparation of urethanes | COVESTRO DEUTSCHLAND AG (DE) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152559-A1 | PROCESS FOR THE PREPARATION OF URETHANES | OGG1, SOD1, DUOX2 | ALDH1A1 1350/4885MEN1 3634/4885KMT2A 674/4885 |
| US-20090275771-A1 | Process for the preparation of urethanes | OGG1, SOD1, DUOX2 | ALDH1A1 1350/4885MEN1 3634/4885KMT2A 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.