Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 4/20 | 0.35 |
| ▸ | F13A1 | P00488 | 3/20 | 0.35 |
| ▸ | TGM1 | P22735 | 3/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.35 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4531900 | 0.96 | GPR119 (0.35) | SMN1; SMN2NPC1RAB9AGPR119TGM2 | |
| SCHEMBL4355151 | 0.88 | TGM2 (0.36) | SMN1; SMN2NPC1RAB9ATGM2F13A1 | |
| SCHEMBL4350023 | 0.87 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9AGPR119TGM2 | |
| SCHEMBL4533901 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1RAB9AGPR119TGM2 | |
| SCHEMBL4526460 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ATGM2F13A1 | |
| SCHEMBL4358448 | 0.85 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9AGPR119TGM2 | |
| Trifluoroacetic Acid SCHEMBL4538218 | 0.84 | TGM2 (0.34) | SMN1; SMN2NPC1RAB9AGPR119TGM2 | |
| SCHEMBL4347881 | 0.84 | GPR119 (0.42) | SMN1; SMN2NPC1RAB9AGPR119TGM2 | |
| SCHEMBL4359263 | 0.81 | TGM2 (0.35) | SMN1; SMN2NPC1RAB9AGPR119TGM2 | |
| SCHEMBL4355670 | 0.80 | TRPV4 (0.38) | SMN1; SMN2NPC1RAB9AGPR119TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |