Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TGM2 | P21980 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350023 | 0.89 | SMN1; SMN2 (0.40) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL4533901 | 0.89 | SMN1; SMN2 (0.39) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL4526460 | 0.88 | SMN1; SMN2 (0.43) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL4354140 | 0.85 | SMN1; SMN2 (0.36) | NPC1RAB9AMMP1MMP2MMP3 | |
| SCHEMBL4355151 | 0.84 | TGM2 (0.36) | NPC1RAB9AHTTMAPTMMP1 | |
| SCHEMBL4347881 | 0.84 | GPR119 (0.42) | NPC1RAB9ASMN1; SMN2TGM2F13A1 | |
| SCHEMBL4359263 | 0.83 | TGM2 (0.35) | NPC1RAB9AMMP1MMP2MMP3 | |
| Trifluoroacetic Acid SCHEMBL4531900 | 0.82 | GPR119 (0.35) | NPC1RAB9AHTTMMP1MMP2 | |
| SCHEMBL4355670 | 0.82 | TRPV4 (0.38) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4351624 | 0.81 | ENPP2 (0.44) | NPC1RAB9AMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |