Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.41 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128613 | 0.82 | CYP3A4 (0.65) | CYP3A4PIK3CAMTORATRPIK3CD | |
| SCHEMBL4357191 | 0.80 | PDE9A (0.44) | CYP3A4SLC2A1SLC2A2SLC2A3SMN1; SMN2 | |
| SCHEMBL4357936 | 0.80 | CYP3A4 (0.41) | CYP3A4SLC2A1SLC2A2SLC2A3SMN1; SMN2 | |
| SCHEMBL304669 | 0.77 | CYP3A4 (0.44) | CYP3A4SLC2A1SLC2A2SLC2A3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1128930 | 0.76 | CYP3A4 (0.41) | CYP3A4SLC2A1SLC2A2SLC2A3SMN1; SMN2 | |
| SCHEMBL1129104 | 0.75 | SMN1; SMN2 (0.43) | CYP3A4SLC2A1SLC2A2SLC2A3SMN1; SMN2 | |
| SCHEMBL4363438 | 0.75 | CYP3A4 (0.49) | CYP3A4SMN1; SMN2KDRBRD4ABL1 | |
| SCHEMBL9006277 | 0.75 | SRC (0.45) | CYP3A4PDE9APIK3CDABL1SRC | |
| SCHEMBL1128747 | 0.74 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL1128588 | 0.73 | CYP3A4 (0.70) | CYP3A4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188098-B2 | GPR119 receptor agonists | HOFFMANN-LA ROCHE INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090286812-A1 | GPR119 Receptor Agonists | ERICKSON SHAWN DAVID | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286812-A1 | GPR119 Receptor Agonists | GPR119, GPR27, GPR139 | CYP3A4 1503/4885SLC2A1 172/4885SLC2A2 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.