Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.39 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363438 | 0.85 | CYP3A4 (0.49) | CYP3A4FLT3EIF2AK3LMNAKDR | |
| SCHEMBL1128198 | 0.82 | CYP3A4 (0.68) | CYP3A4PIK3CGMAPTSRCABL1 | |
| SCHEMBL4354264 | 0.80 | CYP3A4 (0.41) | PDE9ACYP3A4PIK3CGSLC2A1SLC2A2 | |
| SCHEMBL4357936 | 0.80 | CYP3A4 (0.41) | PDE9ACYP3A4SLC2A1SLC2A2SLC2A3 | |
| SCHEMBL9006277 | 0.79 | SRC (0.45) | PDE9ACYP3A4FLT3ALKSRC | |
| SCHEMBL4358920 | 0.79 | BRAF (0.51) | CYP3A4FLT3KDRABL1EGFR | |
| Hydrochloric Acid SCHEMBL1128930 | 0.76 | CYP3A4 (0.41) | PDE9ACYP3A4SLC2A1SLC2A2SLC2A3 | |
| SCHEMBL1128588 | 0.76 | CYP3A4 (0.70) | CYP3A4FLT3 | |
| SCHEMBL304669 | 0.76 | CYP3A4 (0.44) | CYP3A4SLC2A1SLC2A2SLC2A3MAPT | |
| SCHEMBL4358365 | 0.76 | ABL1 (0.57) | CYP3A4FLT3SRCKDRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188098-B2 | GPR119 receptor agonists | HOFFMANN-LA ROCHE INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090286812-A1 | GPR119 Receptor Agonists | ERICKSON SHAWN DAVID | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286812-A1 | GPR119 Receptor Agonists | GPR119, GPR27, GPR139 | PDE9A 528/4885CYP3A4 1503/4885PIP4K2A 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.