Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415410 | 0.78 | AKR1C3 (0.45) | AKR1C3AKR1C2MEN1KMT2AMAPK1 | |
| SCHEMBL3895791 | 0.68 | CASP3 (0.54) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1415795 | 0.68 | ACHE (0.44) | AKR1C3AKR1C2MEN1KMT2AMAPK1 | |
| SCHEMBL1415514 | 0.66 | AKR1C3 (0.46) | AKR1C3AKR1C2MEN1KMT2AHPGD | |
| SCHEMBL1415624 | 0.63 | CASP3 (0.45) | AKR1C3AKR1C2MEN1KMT2AMAPK1 | |
| SCHEMBL1415827 | 0.62 | AKR1C3 (0.45) | AKR1C3AKR1C2MEN1KMT2AKDM1A | |
| SCHEMBL1415497 | 0.62 | DHODH (0.44) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL1416251 | 0.62 | SMN1; SMN2 (0.54) | AKR1C3AKR1C2MEN1KMT2AMAPK1 | |
| SCHEMBL22075935 | 0.61 | MEN1 (0.62) | AKR1C3AKR1C2MEN1KMT2AMAOA | |
| SCHEMBL17629476 | 0.58 | ACHE (0.41) | AKR1C3AKR1C2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | C5, CCNE1, QSOX1 | AKR1C3 785/4885AKR1C2 1511/4885MEN1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.