⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622355 | 0.85 | — | — | |
| Fluoroacetate SCHEMBL19137909 | 0.83 | HMGCR (0.36) | — | |
| SCHEMBL29253076 | 0.81 | — | — | |
| SCHEMBL13792298 | 0.81 | — | — | |
| SCHEMBL19042194 | 0.79 | — | — | |
| Trifluoroacetamide SCHEMBL7739632 | 0.77 | — | — | |
| Trifluoroacetamide SCHEMBL27598858 | 0.77 | — | — | |
| SCHEMBL9722984 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL15128371 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL9957443 | 0.76 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113382990-B | Substituted pyrrolidinamide III | 格吕伦塔尔有限公司 | 2024-11-19 | — | — | CN | claimed |
| EP-4373577-A1 | ACTRII PROTEINS AND USES THEREOF | Acceleron Pharma Inc. (US) | 2024-05-29 | — | — | EP | claimed |
| EP-4358991-A1 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY HYPERTENSION | Acceleron Pharma Inc. (US) | 2024-05-01 | — | — | EP | claimed |
| CN-117957014-A | ActRII proteins and uses thereof | 阿塞勒隆制药公司 | 2024-04-30 | — | — | CN | claimed |
| EP-4351723-A2 | ACTRII PROTEINS AND USES THEREOF | Acceleron Pharma Inc. (US) | 2024-04-17 | — | — | EP | claimed |
| EP-4351626-A2 | ACTRII PROTEINS AND USES THEREOF | Acceleron Pharma Inc. (US) | 2024-04-17 | — | — | EP | claimed |
| CN-117794562-A | ActRII proteins and uses thereof | 阿塞勒隆制药公司 | 2024-03-29 | — | — | CN | claimed |
| EP-4274600-A1 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY HYPERTENSION | Acceleron Pharma Inc. (US) | 2023-11-15 | — | — | EP | claimed |
| CN-117015548-A | Synthetic ursolic acid derivatives and methods of use thereof | 里亚塔医药公司 | 2023-11-07 | — | — | CN | claimed |
| US-20230226146-A1 | ACTRII PROTEINS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION (PAH) | ACCELERON PHARMA INC. | 2023-07-20 | — | — | US | claimed |
| EP-3430903-B1 | SAMPLE FIXATION AND STABILISATION | GOLDSBOROUGH ANDREW SIMON (FR) | 2020-10-21 | — | — | EP | claimed |
| EP-3661931-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-06-10 | — | — | EP | claimed |
| WO-2019027054-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-02-07 | — | — | WO | claimed |
| EP-3430903-A1 | SAMPLE FIXATION AND STABILISATION | Goldsborough, Andrew Simon (FR) | 2019-01-23 | — | — | EP | claimed |
| EP-2961268-B1 | SAMPLE FIXATION AND STABILISATION | GOLDSBOROUGH ANDREW SIMON (FR) | 2018-11-21 | — | — | EP | claimed |
| EP-2961268-A1 | SAMPLE FIXATION AND STABILISATION | Goldsborough, Andrew Simon (FR) | 2016-01-06 | — | — | EP | claimed |
| US-20140295404-A1 | SAMPLE FIXATION AND STABILISATION | RNASSIST LTD. (GB) | 2014-10-02 | — | — | US | claimed |
| WO-2014131906-A1 | SAMPLE FIXATION AND STABILISATION | GOLDSBOROUGH ANDREW SIMON (FR) | 2014-09-04 | — | — | WO | claimed |
| EP-2102169-A1 | INDAZOLYL ESTER AND AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | AstraZeneca AB (SE) | 2009-09-23 | — | — | EP | claimed |
| WO-2008076048-A1 | INDAZOLYL ESTER AND AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | claimed |