SCHEMBL9722984

SCHEMBL9722984

CC(C(N)=O)(C(N)=O)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435447 0.76
SCHEMBL622355 0.76
SCHEMBL1053410 0.75 LMNA (0.33) LMNAALOX15BLMPMP22MAPT
SCHEMBL2727514 0.75 LMNA (0.33) LMNAALOX15BLMPMP22MAPT
SCHEMBL12872355 0.75 LMNA (0.33) LMNAALOX15BLMPMP22MAPT
SCHEMBL28114562 0.75
SCHEMBL13792298 0.73
SCHEMBL29253076 0.73
SCHEMBL3897596 0.73 PDK1 (0.38)
SCHEMBL6439749 0.73 LMNA (0.32) LMNAALOX15BLMPMP22MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5101054-A Antitumor agents DAIKIN INDUSTRIES, LTD. (JP) 1992-03-31 US disclosed
EP-0422242-A1 NEW FLUOROCARBON PLATINUM COMPLEXES DAIKIN INDUSTRIES, LIMITED (JP) 1991-04-17 EP disclosed