Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 10/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129338 | 0.90 | CYP3A4 (0.69) | CYP3A4MTORPIK3CAPIK3CGGPR119 | |
| SCHEMBL2016691 | 0.90 | CYP3A4 (0.54) | CYP3A4MTORPIK3CAPIK3CGMAPK14 | |
| SCHEMBL4360972 | 0.84 | CYP3A4 (0.60) | CYP3A4LMNAHTTHPGDRAB9A | |
| SCHEMBL4352334 | 0.84 | CYP3A4 (0.62) | CYP3A4RAB9ANPC1TP53GAA | |
| SCHEMBL1128417 | 0.82 | CYP3A4 (0.60) | CYP3A4SMN1; SMN2FLT3 | |
| SCHEMBL4353817 | 0.82 | CYP3A4 (0.58) | CYP3A4HTTFLT3 | |
| SCHEMBL4355637 | 0.82 | CYP3A4 (0.60) | CYP3A4GPR119SMN1; SMN2FLT3 | |
| SCHEMBL4354583 | 0.82 | CYP3A4 (0.60) | CYP3A4HPGDTP53SMN1; SMN2FLT3 | |
| SCHEMBL4359112 | 0.81 | CYP3A4 (0.55) | CYP3A4HTTTSHRSMN1; SMN2FLT3 | |
| SCHEMBL2019784 | 0.81 | CYP3A4 (0.79) | CYP3A4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188098-B2 | GPR119 receptor agonists | HOFFMANN-LA ROCHE INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090286812-A1 | GPR119 Receptor Agonists | ERICKSON SHAWN DAVID | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286812-A1 | GPR119 Receptor Agonists | GPR119, GPR27, GPR139 | CYP3A4 1503/4885LMNA 3898/4885HTT 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.