Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.73 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.62 |
| ▸ | PRKCG | P05129 | 2/20 | 0.62 |
| ▸ | PRKCB | P05771 | 2/20 | 0.62 |
| ▸ | PRKCA | P17252 | 2/20 | 0.62 |
| ▸ | PRKCH | P24723 | 2/20 | 0.62 |
| ▸ | PRKCI | P41743 | 2/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 13/20 | 0.48 |
| ▸ | MAOB | P27338 | 13/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13811029 | 0.85 | GSK3B (0.85) | GSK3BPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL4353077 | 0.85 | GSK3B (1.00) | GSK3BPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL14424693 | 0.84 | GSK3B (0.95) | GSK3BPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL5496132 | 0.82 | MAOA (0.54) | GSK3BPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11072984 | 0.82 | GSK3B (0.81) | GSK3BPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL11072864 | 0.81 | GSK3B (0.80) | GSK3BPRKD3PRKCGPRKCBPRKCA | |
| Succinic Acid SCHEMBL4351482 | 0.81 | GSK3B (0.88) | GSK3BPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL4348850 | 0.81 | GSK3B (0.77) | GSK3BPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL6157510 | 0.78 | ESR1 (0.63) | GSK3BPRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL5705813 | 0.77 | ESR1 (0.75) | GSK3BPRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809368-B2 | Compounds affecting gap junction activity | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2014-08-19 | — | — | US | disclosed |
| US-20090143425-A1 | COMPOUNDS AFFECTING GAP JUNCTION ACTIVITY | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-06-04 | — | — | US | disclosed |
| WO-2007127930-A2 | COMPOUNDS AFFECTING GAP JUNCTION ACTIVITY | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143425-A1 | COMPOUNDS AFFECTING GAP JUNCTION ACTIVITY | GJB2, GJA1, GAP43 | GSK3B 1455/4885PRKD3 1619/4885PRKCG 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.