Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345832 | 0.87 | GAA (0.36) | PDE2AVNN1PIK3C3HPGD | |
| SCHEMBL4347126 | 0.69 | TDP1 (0.53) | ALDH1A1HPGD | |
| SCHEMBL4346476 | 0.68 | HPGD (0.61) | ALDH1A1HPGD | |
| SCHEMBL4356080 | 0.68 | HPGD (0.41) | ALDH1A1HPGD | |
| SCHEMBL4354045 | 0.65 | KMT2A (0.44) | ALDH1A1HPGD | |
| SCHEMBL4354896 | 0.65 | HPGD (0.34) | HPGD | |
| SCHEMBL4351695 | 0.64 | KDM4E (0.49) | ALDH1A1HPGD | |
| SCHEMBL4347243 | 0.64 | MAPT (0.42) | ALDH1A1HPGD | |
| SCHEMBL24019233 | 0.63 | ATM (0.43) | ALDH1A1HPGD | |
| SCHEMBL4350380 | 0.62 | FASN (0.34) | ALDH1A1PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | claimed |
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | disclosed |