SCHEMBL4354899

SCHEMBL4354899

C=C[Si](C=C)(O[Si](O)(O)c1ccccc1)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94036 0.85 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL296744 0.79 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL12302824 0.79 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL3481365 0.79 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL17069893 0.78 ESR1 (0.37) ALDH1A1TSHR
SCHEMBL3482271 0.78 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL1245805 0.78 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL336006 0.76 ESR1 (0.32) ALDH1A1TSHR
SCHEMBL13172440 0.76 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL3482068 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7592399-B2 vinyldimethylsiloxy-end-capped dimethylsiloxane-diphenylsiloxane copolymer; methylhydrogenpolysiloxane; 2-ethylhexyl alcohol-modified chloroplatinic acid catalyst; hydrogenated bisphenol A modified with substituted or unsubstituted hydrocarbon groups or silyl groups; an aluminum base curing catalyst SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-09-22 US disclosed
US-20070142574-A1 vinyldimethylsiloxy-end-capped dimethylsiloxane-diphenylsiloxane copolymer; methylhydrogenpolysiloxane; 2-ethylhexyl alcohol-modified chloroplatinic acid catalyst; hydrogenated bisphenol A modified with substituted or unsubstituted hydrocarbon groups or silyl groups; an aluminum base curing catalyst SHIN-ETSU CHEMICAL CO., LTD. 2007-06-21 US disclosed