SCHEMBL336006

SCHEMBL336006

C=C[Si](C=C)(O[Si](C)(C)c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94036 0.85 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL15544196 0.84 ESR1 (0.32) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL247510 0.82 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL5373913 0.82 ESR1 (0.33) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL5348061 0.80 ESR1 (0.32) ESR1ESR2ALDH1A1TSHRMAPT
SCHEMBL4440802 0.79
SCHEMBL296744 0.79 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL3481365 0.79 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL12302824 0.79 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL2600705 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112625449-B Curable composition, cured product thereof, and semiconductor device 信越化学工业株式会社 2023-09-05 CN claimed
CN-104592932-A High-power LED packaging adhesive composition INST CHEMICAL MATERIAL CHINA ACADEMY ENGINEERING PHYSICS 2015-05-06 CN claimed
JP-4409286-B2 2010-02-03 JP claimed
US-20060079099-A1 Ultra low k plasma enhanced chemical vapor deposition processes using a single bifunctional precursor containing both a SiCOH matrix functionality and organic porogen functionality INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-04-13 US claimed
JP-2004536920-A 2004-12-09 JP claimed
EP-1414893-A1 ROOM-TEMPERATURE-CURABLE ORGANOPOLYSILOXANE COMPOSITION Dow Corning Toray Silicone Co., Ltd. (JP) 2004-05-06 EP claimed
WO-2003010227-A1 ROOM-TEMPERATURE-CURABLE ORGANOPOLYSILOXANE COMPOSITION DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-02-06 WO claimed
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2025-05-13 US disclosed
CN-112625449-B Curable composition, cured product thereof, and semiconductor device 信越化学工业株式会社 2023-09-05 CN disclosed
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-08-03 US disclosed
EP-3590596-B1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-07-12 EP disclosed
EP-3689891-B1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-03-01 EP disclosed
CN-112480682-B Addition-curable silicone composition, cured product thereof, sheet, and optical element 信越化学工业株式会社 2023-02-17 CN disclosed
EP-1174435-A2 Process for preparing complexes between platinum and alkenylsiloxane compounds, in particular platinum-divinyltetramethylsiloxane W.C. Heraeus GmbH & Co. KG (DE) 2002-01-23 EP disclosed
US-5789334-A PLATINUM CATALYST, DISILOXANE, STORAGE STABILITY, DIMETHYLDIVINYLDIPHENYLDISILOXANE DOW CORNING TORAY SILICONE CO., LTD. (JP) 1998-08-04 US disclosed
EP-0761761-A1 Microparticle catalysts for hydrosilylation reactions and thermosetting silicone compositions containing said catalyst Dow Corning Toray Silicone Company Ltd. (JP) 1997-03-12 EP disclosed
EP-0712432-A1 LIGHT MODULATING DEVICE HAVING A SILICON-CONTAINING MATRIX MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-22 EP disclosed
EP-0323085-B1 Removal of polyfunctional silanes from organosilanes DOW CORNING (US) 1994-03-09 EP disclosed
EP-0323085-A2 Removal of polyfunctional silanes from organosilanes DOW CORNING CORPORATION (US) 1989-07-05 EP disclosed
US-4782172-A Removal of polyfunctional silanes from organosilanes DOW CORNING CORPORATION (US) 1988-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction H1-0, HVCN1, H1-2 ESR1 1311/4885ESR2 1580/4885ALDH1A1 1437/4885
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION H1-0, HVCN1, H1-2 ESR1 1311/4885ESR2 1580/4885ALDH1A1 1437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.