Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 4/20 | 0.39 |
| ▸ | USP47 | Q96K76 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355400 | 1.00 | LMNA (0.40) | LMNAHTTALDH1A1MAPK1USP7 | |
| SCHEMBL3772527 | 0.81 | CYP1A2 (0.36) | LMNAHTTALDH1A1MAPK1MAPT | |
| SCHEMBL3470549 | 0.81 | CYP1A2 (0.36) | LMNAHTTALDH1A1MAPK1MAPT | |
| SCHEMBL7680313 | 0.75 | ALDH1A1 (0.46) | ALDH1A1VCAM1MAPTMEN1KMT2A | |
| SCHEMBL2712274 | 0.75 | GPR35 (0.57) | LMNAHTTALDH1A1MAPK1VCAM1 | |
| SCHEMBL7680328 | 0.75 | ALDH1A1 (0.46) | ALDH1A1VCAM1MAPTMEN1KMT2A | |
| SCHEMBL2712279 | 0.75 | GPR35 (0.57) | LMNAHTTALDH1A1MAPK1VCAM1 | |
| SCHEMBL13706812 | 0.75 | ALDH1A1 (0.41) | LMNAHTTALDH1A1MAPK1USP7 | |
| SCHEMBL4362286 | 0.72 | AKR1B1 (0.42) | LMNAHTTALDH1A1MAPK1USP7 | |
| SCHEMBL4362290 | 0.72 | AKR1B1 (0.42) | LMNAHTTALDH1A1MAPK1USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |