Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355152 | 0.90 | CHRM2 (0.38) | ALDH1A1USP30PIK3CANPC1CACNA1B | |
| SCHEMBL4347925 | 0.84 | USP30 (0.40) | USP30KDM1APIK3CAPTGS2GPR119 | |
| SCHEMBL4537918 | 0.83 | PTPN2 (0.43) | ALDH1A1PIK3CAPOLBCA1CA2 | |
| SCHEMBL4356473 | 0.83 | PTPN2 (0.43) | ALDH1A1PIK3CAPOLBCA1CA2 | |
| SCHEMBL4349922 | 0.83 | PTPN2 (0.43) | ALDH1A1PIK3CAPOLBCA1CA2 | |
| SCHEMBL4353588 | 0.82 | PIK3CA (0.43) | USP30PIK3CACYP2C9GPR119 | |
| SCHEMBL4355702 | 0.82 | PIK3CA (0.37) | USP30PIK3CAPTGS2GPR119 | |
| SCHEMBL4357301 | 0.82 | PIK3CA (0.35) | USP30KDM1APIK3CAFASNPTGS2 | |
| SCHEMBL4347874 | 0.81 | KDM1A (0.41) | USP30KDM1APIK3CANPC1GPR119 | |
| SCHEMBL4353473 | 0.81 | PTPN2 (0.47) | ALDH1A1POLBCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |