Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357301 | 0.87 | PIK3CA (0.35) | PIK3CAPTGS2GPR119LRRK2USP30 | |
| SCHEMBL4356151 | 0.87 | GAA (0.42) | PIK3CAGPR119 | |
| SCHEMBL4355152 | 0.86 | CHRM2 (0.38) | PIK3CAUSP30CHRM2 | |
| SCHEMBL4353588 | 0.85 | PIK3CA (0.43) | PIK3CAGPR119USP30 | |
| SCHEMBL4349922 | 0.84 | PTPN2 (0.43) | PIK3CA | |
| SCHEMBL4356473 | 0.84 | PTPN2 (0.43) | PIK3CA | |
| SCHEMBL4537918 | 0.84 | PTPN2 (0.43) | PIK3CA | |
| SCHEMBL4348569 | 0.83 | GPR119 (0.39) | PIK3CAPTGS2GPR119USP30CYP11B2 | |
| SCHEMBL4535480 | 0.83 | LMNA (0.42) | PIK3CAGPR119USP30CYP11B2 | |
| SCHEMBL4347925 | 0.82 | USP30 (0.40) | PIK3CAPTGS2GPR119LRRK2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |