Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 5/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420569 | 0.83 | CYP2D6 (0.47) | CYP2C19MPOHTR2B | |
| SCHEMBL13497613 | 0.81 | GPR84 (0.46) | MPOGPR84SLC6A4 | |
| SCHEMBL13540046 | 0.80 | GPR84 (0.43) | MPOGPR84SLC6A4HTR2B | |
| SCHEMBL26202021 | 0.76 | HTR2A (0.55) | MPOGPR84TSHRHTR7HTR2B | |
| SCHEMBL1537936 | 0.76 | HPGD (0.64) | HPGDCYP2C19MPOSLC6A4DRD3 | |
| SCHEMBL10078603 | 0.76 | CDK2 (0.53) | HPGDCYP2C19GPR17SLC6A4FFAR1 | |
| SCHEMBL29902243 | 0.73 | MPO (0.76) | HPGDCYP2C19MPOGPR84TSHR | |
| SCHEMBL5637957 | 0.73 | HTR2A (0.63) | HPGDCYP2C19MPOGPR84TSHR | |
| SCHEMBL3655654 | 0.73 | MPO (0.76) | HPGDCYP2C19MPOGPR84TSHR | |
| SCHEMBL3416926 | 0.72 | TDO2 (0.57) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009153307-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |