Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481449 | 0.80 | MAPK1 (0.40) | POLBTSHRMAPTKMT2AMAPK1 | |
| SCHEMBL6901115 | 0.70 | POLB (0.69) | POLBALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL5717558 | 0.69 | ALDH1A1 (0.73) | POLBALDH1A1TDP1TSHRMAPT | |
| SCHEMBL237337 | 0.69 | ALDH1A1 (0.66) | POLBALDH1A1TSHRKMT2ARAB9A | |
| SCHEMBL2223592 | 0.68 | KDM4E (0.61) | POLBALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL11107537 | 0.68 | KDM4E (0.80) | POLBTDP1KDM4EMAPTHIF1A | |
| SCHEMBL7074467 | 0.67 | ALDH1A1 (1.00) | POLBALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL1422592 | 0.66 | — | — | |
| SCHEMBL512220 | 0.66 | — | — | |
| SCHEMBL936016 | 0.66 | HIF1A (0.69) | KDM4EMAPTHIF1ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |