Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.69 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.69 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | KDM5A | P29375 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11175012 | 0.93 | HIF1A (0.61) | HIF1AKDM4EMAPTSLC22A6SLC22A8 | |
| Glycine SCHEMBL936464 | 0.93 | HIF1A (0.66) | HIF1AKDM4EMAPTSLC22A6SLC22A8 | |
| SCHEMBL13593287 | 0.93 | HIF1A (0.61) | HIF1AKDM4EMAPTSLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL8957458 | 0.92 | HIF1A (0.59) | HIF1AKDM4EMAPTSLC22A6SLC22A8 | |
| SCHEMBL11107537 | 0.91 | KDM4E (0.80) | HIF1AKDM4EMAPTSLC22A6SLC22A8 | |
| Benzoic Acid SCHEMBL15670619 | 0.89 | HIF1A (0.57) | HIF1AKDM4EMAPTSLC22A6SLC22A8 | |
| SCHEMBL24224263 | 0.85 | KDM4E (0.71) | HIF1AKDM4EMAPTSLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL7486 | 0.83 | GAA (0.68) | HIF1AKDM4EMAPTSLC22A6SLC22A8 | |
| SCHEMBL22030672 | 0.83 | GAA (0.68) | HIF1AKDM4EMAPTSLC22A6SLC22A8 | |
| Hippuric Acid SCHEMBL428479 | 0.83 | GAA (0.68) | HIF1AKDM4EMAPTSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3869192-B1 | METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE | HUMAN METABOLOMICS INST INC (CN) | 2026-05-13 | — | — | EP | claimed |
| US-12584924-B2 | Compositions and methods for diagnosing and treating chronic kidney disease | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2026-03-24 | — | — | US | claimed |
| US-20250258146-A1 | QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP | HUMAN METABOLOMICS INSTITUTE INC. (CN) | 2025-08-14 | — | — | US | claimed |
| US-20250236901-A1 | METHOD OF DETECTING A MICROORGANISM HAVING HIPPURICASE ACTIVITY | BIOSYNTH AG (CH) | 2025-07-24 | — | — | US | claimed |
| EP-4581047-A1 | TOXIN-BINDER FOR HEMODIALYSIS | Universität Hamburg (DE) | 2025-07-09 | — | — | EP | claimed |
| WO-2025123045-A1 | PREDICTIVE AND DIAGNOSTIC SCREENING METHODS FOR ENDOMETRIAL CANCER | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2025-06-12 | — | — | WO | claimed |
| US-12292445-B2 | Methods of selecting subjects for treatment with metabolomic modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-05-06 | — | — | US | claimed |
| EP-4511504-A1 | METHOD OF DETECTING A MICROORGANISM HAVING HIPPURICASE ACTIVITY | Biosynth AG (CH) | 2025-02-26 | — | — | EP | claimed |
| US-20250051551-A1 | IMPROVED POLYMER COMPOSITES | WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) | 2025-02-13 | — | — | US | claimed |
| CN-119291059-A | Screening method for metabolic markers for distinguishing non-colorectal cancer diseases from colorectal cancer and application of screening method | 哈尔滨脉图精准技术有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-104204798-A | Biomarkers for bladder cancer and methods using the same | METABOLON INC | 2014-12-10 | — | — | CN | claimed |
| EP-2776832-A1 | BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME | Metabolon, Inc. (US) | 2014-09-17 | — | — | EP | claimed |
| US-20140224737-A1 | MOLECULARLY IMPRINTED POLYMERS FOR ELIMINATING METABOLITES | FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (DE) | 2014-08-14 | — | — | US | claimed |
| WO-2013070839-A1 | BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME | METABOLON, INC. (US) | 2013-05-16 | — | — | WO | claimed |
| US-20130011364-A1 | MOLECULARLY IMPRINTED POLYMERS FOR ELIMINATING METABOLITES | FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (DE) | 2013-01-10 | — | — | US | claimed |
| WO-2011010104-A1 | METHODS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-01-27 | — | — | WO | claimed |
| WO-2011010103-A1 | METHODS AND USES | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-01-27 | — | — | WO | claimed |
| EP-0754760-B1 | Method and reagent for detecting peroxidase or hydrogen peroxide | YAMAGATA PUBLIC CORP DEV IND (JP) | 2002-11-13 | — | — | EP | claimed |
| US-5780257-A | PRODUCING PHENOXY RADICALS FROM P-SUBSTITUTED PHENOL COMPOUNDS, TRANSFERRING ELECTRONS FROM PHENOXY COMPOUND TO HYDROXY AMINE COMPOUND, MEASURING ELECTRON SPIN RESONANCE | YAMAGATA TECHNOPOLIS FOUNDATION (JP) | 1998-07-14 | — | — | US | claimed |
| EP-0754760-A1 | Method and reagent for detecting peroxidase or hydrogen peroxide | YAMAGATA TECHNOPOLIS FOUNDATION (JP) | 1997-01-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12584924-B2 | Compositions and methods for diagnosing and treating chronic kidney disease | GLS, AADAT, FGF23 | HIF1A 37/4885KDM4E 124/4885MAPT 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.