Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356081 | 1.00 | MMP2 (0.44) | MMP2SLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL13821332 | 0.79 | CTSS (0.56) | SLC1A3SLC1A2SLC1A1TDP1HSD17B10 | |
| SCHEMBL2029903 | 0.79 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1ALOX5TDP1 | |
| SCHEMBL2029905 | 0.79 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1ALOX5TDP1 | |
| SCHEMBL2035900 | 0.79 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1ALOX5TDP1 | |
| SCHEMBL3319872 | 0.75 | ALOX5 (0.44) | SLC1A3SLC1A2SLC1A1ALOX5TDP1 | |
| SCHEMBL180118 | 0.75 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1ALOX5TDP1 | |
| SCHEMBL218877 | 0.75 | MMP2 (0.73) | MMP2PKM | |
| SCHEMBL1663153 | 0.75 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1ALOX5TDP1 | |
| SCHEMBL599915 | 0.75 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1ALOX5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |