SCHEMBL4356446

SCHEMBL4356446

CCCCc1nc(CO)c(CO)[nH]1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
GPR84 Q9NQS5 5/20 0.39
PARP1 P09874 1/20 0.37
GSK3B P49841 1/20 0.35
PI4KA P42356 1/20 0.33
PI4K2B Q8TCG2 1/20 0.33
PI4K2A Q9BTU6 1/20 0.33
PI4KB Q9UBF8 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9081675 0.95 GPR84 (0.45) ALDH1A1MAPK1GPR84PI4KAPI4K2B
SCHEMBL9081811 0.93 GPR84 (0.46) ALDH1A1MAPK1GPR84PI4KAPI4K2B
SCHEMBL4356039 0.93 GPR84 (0.46) ALDH1A1MAPK1GPR84PI4KAPI4K2B
SCHEMBL9082364 0.93 GPR84 (0.46) ALDH1A1MAPK1GPR84PI4KAPI4K2B
SCHEMBL9082048 0.93 GPR84 (0.46) ALDH1A1MAPK1GPR84PI4KAPI4K2B
SCHEMBL21248457 0.93 GPR84 (0.46) ALDH1A1MAPK1GPR84PI4KAPI4K2B
SCHEMBL9082927 0.93 GPR84 (0.46) ALDH1A1MAPK1GPR84PI4KAPI4K2B
SCHEMBL9081998 0.93 GPR84 (0.46) ALDH1A1MAPK1GPR84PI4KAPI4K2B
SCHEMBL4356818 0.89 GLA (0.35) ALDH1A1MAPK1GPR84
SCHEMBL4353447 0.80 ADORA1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7614145-B2 Method for manufacturing multilayer circuit board and resin base material ZEON CORPORATION (JP) 2009-11-10 US disclosed
US-20080217617-A1 Thin Film Transistor, Wiring Board and Methods of Manufacturing the Same ZEON CORPORATION (JP) 2008-09-11 US disclosed
US-20050153059-A1 Partial plating method, partially-plated resin base, method for manufacturing multilayered circuit board ZEON CORPORATION (JP) 2005-07-14 US disclosed
US-20040237295-A1 Multilayer circuit board and resin base material, and its production method ZEON CORPORATION (JP) 2004-12-02 US disclosed
EP-0611758-B1 Process for synthesizing 4-halo-5(hydroxymethyl) imidazole compounds and certain novel 4-halo-5(hydroxymethyl) imidazole compounds SHIKOKU CHEM (JP) 1996-10-16 EP disclosed
US-5514811-A Process for synthesizing 4-halo-5-(hydroxymethyl) imidazole compounds SHIKOKU CHEMICALS CORPORATION (JP) 1996-05-07 US disclosed
EP-0611758-A1 Process for synthesizing 4-halo-5(hydroxymethyl) imidazole compounds and certain novel 4-halo-5(hydroxymethyl) imidazole compounds SHIKOKU CHEMICALS CORPORATION (JP) 1994-08-24 EP disclosed
US-5281615-A Hypotensive agents G. D. SEARLE & CO. (US) 1994-01-25 US disclosed
US-5104891-A CYCLOHEPTIMIDAZOLONE COMPOUNDS AS ANGIOTENSIN II ANTAGONISTS FOR CONTROL OF HYPERTENSION G. D. SEARLE & CO. (US) 1992-04-14 US disclosed
WO-1991019715-A1 1H-SUBSTITUTED-IMIDAZO[4,5-d]PYRIDAZINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS G.D. SEARLE & CO. (US) 1991-12-26 WO disclosed
EP-0432737-A1 Cycloheptimidazolone compounds as angiotensin II antagonists for control of hypertension G.D. Searle & Co. (US) 1991-06-19 EP disclosed