Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9082364 | 1.00 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGDPI4KA | |
| SCHEMBL9081811 | 1.00 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGDPI4KA | |
| SCHEMBL4356039 | 1.00 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGDPI4KA | |
| SCHEMBL9082048 | 1.00 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGDPI4KA | |
| SCHEMBL21248457 | 1.00 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGDPI4KA | |
| SCHEMBL9082927 | 1.00 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGDPI4KA | |
| SCHEMBL9081675 | 0.98 | GPR84 (0.45) | GPR84ALDH1A1PKMHPGDPI4KA | |
| SCHEMBL4356446 | 0.93 | ALDH1A1 (0.42) | GPR84ALDH1A1PKMHPGDPI4KA | |
| SCHEMBL4356818 | 0.85 | GLA (0.35) | GPR84ALDH1A1MAPK1 | |
| SCHEMBL129 | 0.81 | GPR84 (0.45) | GPR84ALDH1A1PKMHPGDPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611758-B1 | Process for synthesizing 4-halo-5(hydroxymethyl) imidazole compounds and certain novel 4-halo-5(hydroxymethyl) imidazole compounds | SHIKOKU CHEM (JP) | 1996-10-16 | — | — | EP | disclosed |
| US-5514811-A | Process for synthesizing 4-halo-5-(hydroxymethyl) imidazole compounds | SHIKOKU CHEMICALS CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0611758-A1 | Process for synthesizing 4-halo-5(hydroxymethyl) imidazole compounds and certain novel 4-halo-5(hydroxymethyl) imidazole compounds | SHIKOKU CHEMICALS CORPORATION (JP) | 1994-08-24 | — | — | EP | disclosed |