Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 15/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347874 | 0.83 | KDM1A (0.41) | KMT2AUSP30 | |
| SCHEMBL4347925 | 0.81 | USP30 (0.40) | USP30KCNH2 | |
| SCHEMBL4529650 | 0.79 | KMT2A (0.39) | ALDH1A1KMT2AUSP30 | |
| SCHEMBL4360375 | 0.79 | KDM1A (0.39) | ALDH1A1KMT2AUSP30CYP2D6 | |
| SCHEMBL4353455 | 0.78 | KDM1A (0.43) | ALDH1A1KMT2AUSP30 | |
| SCHEMBL4531768 | 0.78 | KDM1A (0.38) | KMT2AUSP30 | |
| SCHEMBL4349922 | 0.78 | PTPN2 (0.43) | ALDH1A1 | |
| SCHEMBL4537918 | 0.78 | PTPN2 (0.43) | ALDH1A1 | |
| SCHEMBL4356473 | 0.78 | PTPN2 (0.43) | ALDH1A1 | |
| SCHEMBL4353588 | 0.77 | PIK3CA (0.43) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |