Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.32 |
| ▸ | KMO | O15229 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.30 |
| ▸ | EIF4E | P06730 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462675 | 0.91 | CFTR (0.34) | CFTRPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL3326459 | 0.88 | KDM4E (0.37) | CFTRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2469848 | 0.83 | PPARA (0.35) | KMOCYP3A4TDP1EIF4E | |
| SCHEMBL3843276 | 0.83 | KMO (0.35) | CFTRKMOCYP3A4TDP1EIF4E | |
| SCHEMBL2464683 | 0.83 | MEN1 (0.34) | KMOCYP3A4TDP1EIF4E | |
| SCHEMBL17623448 | 0.82 | KMO (0.35) | KMOCYP3A4TDP1EIF4E | |
| SCHEMBL16076564 | 0.82 | KMO (0.36) | KMOCYP3A4TDP1EIF4E | |
| SCHEMBL190443 | 0.81 | DHODH (0.34) | KMOCYP3A4TDP1EIF4E | |
| SCHEMBL115379 | 0.81 | ALDH1A1 (0.40) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL29405327 | 0.81 | ALDH1A1 (0.40) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | disclosed |
| CN-102731382-A | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC | 2012-10-17 | — | — | CN | disclosed |
| CN-102731381-A | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC | 2012-10-17 | — | — | CN | disclosed |
| CN-101360713-B | 6- (polysubstituted aryl) -4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC | 2012-08-15 | — | — | CN | disclosed |
| CN-102300459-A | Herbicide-safener combination | — | 2011-12-28 | — | — | CN | disclosed |
| EP-2060566-A1 | Poly-substituted aryls | Dow AgroSciences LLC (US) | 2009-05-20 | — | — | EP | disclosed |
| US-7498468-B2 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2009-03-03 | — | — | US | disclosed |
| CN-101360713-A | 6- (polysubstituted aryl) -4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2009-02-04 | — | — | CN | disclosed |
| EP-1973881-A2 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2008-10-01 | — | — | EP | disclosed |
| US-20080051596-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080045734-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-02-21 | — | — | US | disclosed |
| US-7314849-B2 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-20070179060-A1 | 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2007-08-02 | — | — | US | disclosed |
| WO-2007082098-A2 | 6-(POLY-SUBSTITUTED ARYL)-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045734-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | CFTR 3965/4885PRKAB2 4742/4885PRKAG1 4593/4885 |
| US-20070179060-A1 | 6-(Poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | CFTR 3965/4885PRKAB2 4742/4885PRKAG1 4593/4885 |
| US-20080051596-A1 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides | AAAS, DDT, AADAC | CFTR 3965/4885PRKAB2 4742/4885PRKAG1 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.